We're diving into a topic that’s generating a lot of buzz in the T1D community: GLP-1s. To break down what these medications actually do, what the research says, and how they might benefit people with type 1 diabetes, we're joined by pediatric endocrinologist Dr. Justin Gregory. We explore what GLP-1s are, how they work in the body, and why they’re attracting so much attention in T1D care. Dr. Gregory shares insights on their effects on blood sugar, insulin needs, and insulin sensitivity (and whether those benefits are purely tied to weight loss or something more direct). Whether you've only seen GLP-1s mentioned on social media or you've already started a conversation with your healthcare team, this episode brings clarity to the hype and the hope. Don't miss this conversation - we’re answering all the questions the T1D community has been waiting for.
Quick Takeaways:
- Everything you need to know about GLP-1s: What they are, who they are meant for & why they are getting so much hype
- The impact these medications have on T1D: Blood sugar, insulin needs, insulin sensitivity, and more
- Breaking down the risks: Direct impact on T1D (blood sugars, insulin needs, etc.) and side effects of long-term use
- How GLP-1s are being prescribed off-label to type 1s and the important conversations people with T1D should have with their provider before starting them
Timestamps:
- [03:13] Dr. Gregory’s journey into Endocrinology
- [03:37] “Diagnosed with T1D and I was told, your Air Force career is over…”
- [05:21] “My research says, what is the cost of putting too much insulin in the wrong place?”
- [09:43] One of the most underappreciated aspects of T1D: Insulin sensitivity
- [XX:XX] “Insulin sensitivity is 30 to 50% lower in type 1 diabetes compared to mass control.”
- [12:34] How to determine your insulin sensitivity (and increase it)
- [21:13] The breakdown of GLP-1s
- [23:25] Understanding GLP-1s efficacy in T1D
- [27:09] Who will benefit from these medications vs. who might hurt
- [30:41] Insulin resistance with a healthy BMI: How is it possible?
- [34:42] Prescribing these medications to children
- [38:34] How GLP-1s could be used for the newly diagnosed T1D population
- [39:00] Dr. Gregory’s expectations for the future and evolution of these medications
- [41:06] Pregnancy + GLP-1s
- [46:24] “When you come off of it, if you're not staying on it forever, what happens?”
What to do now:
- Follow me @lauren_bongiorno and @riselyhealth on Instagram to stay in the loop when new episodes drop.
- Apply for coaching and talk to our team so you can reclaim the life you deserve.
- Join the PEP (Parents Empowering Parents) Squad, a Facebook group created by the Diabetes Research Institute. This is a place where caregivers of kids with T1D can share stories, ask questions, and learn more about how to get involved with research, advocacy, and fundraising through DRI.
